Summary for clan SS

Summary Alignment Structure Literature
HistoryMEROPS 7.2 (14 October 2005)
DescriptionSerine nucleophile; catalytic residues in the order Ser, Glu, His
Contents of clanClan SS contains enzymes that cleave amide bonds between L- and D-amino acids that occur in bacterial peptidoglycan.
EvidenceThe structure of the type peptidase of family S66 is unlike that known for any other peptidase (Korza & Bochtler, 2005).
Catalytic mechanism(See family S66.)
Peptidase activity(See family S66.)
Protein foldSee Korza & Bochtler (2005)).
Homologous non-peptidase familiesProteins with similar folds, detected by querying the DALI server, are the biological subunit of l-fucose isomerase from Escherichia coli and the hypothetical protein MJ0783 from Methanocaldococcus jannaschii.
Other databases SCOP141986


Family Family Type Peptidase Structure
S66 murein tetrapeptidase LD-carboxypeptidase ({Pseudomonas}-type) (Pseudomonas aeruginosa) Yes

Distribution of clan SS among Kingdoms of Organisms