Family C23


Summary Holotypes Alignment Tree Genomes Literature

Summary for family C23

Family type peptidaseC23.001 - carlavirus peptidase (apple stem pitting virus), MEROPS Accession MER0002101 (peptidase unit: 1192-1288)
Content of familyPeptidase family C23 contains cysteine endopeptidases of single-stranded RNA viruses.
History Identifier created: Perspect.Drug Discov.Des. 6:1-11 (1996)
Catalytic typeCysteine
Active site residuesC1202 H1283 
Active siteCys1202 and His1283 are catalytic residues (Lawrence et al., 1995).
Activities and specificitiesLike other, similar peptidases of plant viruses, the peptidases of family C23 cleave in cis but not in trans, and an AlaAsp cleavage site has been tentatively identified (Lawrence et al., 1995).
Molecular structure
Basis of clan assignmentActive site residues for members of this family and family C1 occur in the same order in the sequence: C, H.
Distribution of family Bacteria -  
Archaea -  
Protozoa -  
Fungi -  
Plants -  
Animals -  
Viruses details  
Biological functionsThe peptidases of the family are necessary for the processing of the carlavirus polyproteins.
Statistics for family C23Sequences:44
Identifiers with PDB entries:0
Downloadable files Sequence library (FastA format)
Sequence alignment (FastA format)
Phylogenetic tree (Newick format)
Peptidases and Homologues MEROPS ID Structure
carlavirus peptidaseC23.001-
family C23 unassigned peptidasesunassigned-