|Family type peptidase||S69.001 - Tellina virus 1 VP4 peptidase (Tellina virus 1), MEROPS Accession MER0099995 (peptidase unit: 619-831)|
|Content of family||Family S69 contains viral endopeptidases.|
Identifier created: MEROPS 8.0 (8 January 2008)|
Tellina virus 1, named after its host the marine bivalve mollusk Tellina tenuis, is a member of a divergent clade of birnaviruses, and its VP4 peptidase differs so much from those of other birnaviruses, in family S50, as to require the separate family S69.
|Active site residues||S738 K777 |
|Active site||The catalytic Ser/Lys dyad identified by Nobiron et al. (2008) by mutagenesis does not possess the Gly-X-Ser signature found in family S50 and many other serine peptidases (see the Alignment).|
|Activities and specificities||Alanyl bonds are cleaved in the processing of a viral polyprotein (Nobiron et al., 2008; see the Substrates page).|
|Molecular structure||It is reasonable to assume that the fold is similar to those in family S50, and family S69 is also assigned to clan SJ.|