Summary for peptidase A01.015: barrierpepsin

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates


MEROPS Namebarrierpepsin
Other namesalpha-factor protease, Bar g.p. (Saccharomyces cerevisiae), Bar1 peptidase, barrier proteinase
Domain architecture
MEROPS Classification
Classification Clan AA >> Subclan (none) >> Family A1 >> Subfamily A >> A01.015
Holotypebarrierpepsin (Saccharomyces cerevisiae), Uniprot accession P12630 (peptidase unit: 25-396), MERNUM MER0001428
History Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.
Catalytic typeAspartic
PeplistIncluded in the Peplist with identifier PL00013
NC-IUBMBSubclass 3.4 (Peptidases) >> Sub-subclass 3.4.23 (Aspartic endopeptidases) >> Peptidase
EnzymologyBRENDA database
Proteolytic eventsCutDB database (1 cleavage)
PhysiologyCleaves alpha factor of Saccharomyces cerevisiae, and so affects mating of the yeast (Barkai et al., 1998).