Summary for peptidase A01.037: canditropsin

Summary Alignment Sequences Sequence features Distribution Structure Literature Substrates Inhibitors


MEROPS Namecanditropsin
Other namesCandida tropicalis secreted aspartic protease (SAPT)
Domain architecture
MEROPS Classification
Classification Clan AA >> Subclan (none) >> Family A1 >> Subfamily A >> A01.037
Holotypecanditropsin (Candida tropicalis), Uniprot accession Q00663 (peptidase unit: 54-384), MERNUM MER0000931
History Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.
Catalytic typeAspartic
PeplistIncluded in the Peplist with identifier PL00428
NC-IUBMBNot yet included in IUBMB recommendations.
Proteolytic eventsCutDB database (2 cleavages)
Pharmaceutical relevanceBelieved to contribute to the virulence of Candida tropicalis in infection of mammals (Zaugg et al., 2001). Hence, a possible drug target for candidiasis.