Summary for peptidase A01.067: candidapepsin SAP9

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates Inhibitors

 

Names
MEROPS Namecandidapepsin SAP9
Other namessecreted aspartic proteinase 9 (Candida albicans), SAP6 (Metschnikowia reukaufii), SAP9 g.p. (Candida albicans), SAP9 proteinase (Candida albicans)
Domain architecture
MEROPS Classification
Classification Clan AA >> Subclan (none) >> Family A1 >> Subfamily A >> A01.067
Holotypecandidapepsin SAP9 (Candida albicans), Uniprot accession O42779 (peptidase unit: 45-482), MERNUM MER0005351
History Identifier created: MEROPS 6.3 (23 June 2003)
Activity
Catalytic typeAspartic
NC-IUBMBNot yet included in IUBMB recommendations.
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/-/klrScissile bond-/-/-/- (based on 17 cleavages)
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Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 2 1 1 0 0 0 2 2
Pro 1 0 1 0 0 1 1 2
Ala 0 1 3 0 1 3 1 2
Val 1 2 1 0 1 3 2 0
Leu 2 1 1 3 0 0 1 0
Ile 1 1 0 0 1 0 1 0
Met 0 1 0 0 0 0 1 0
Phe 1 2 1 1 2 2 0 1
Tyr 2 2 0 1 0 1 0 0
Trp 0 0 0 0 0 0 0 0
Ser 0 2 3 1 2 1 0 2
Thr 1 0 1 0 0 0 1 0
Cys 1 2 1 0 2 2 0 0
Asn 1 0 0 0 2 0 0 0
Gln 0 0 0 1 1 1 0 2
Asp 0 0 1 0 1 1 2 3
Glu 3 0 0 0 2 0 1 1
Lys 0 1 2 7 2 0 3 2
Arg 0 0 1 3 0 1 0 0
His 1 1 0 0 0 1 1 0