Summary for peptidase A02.063: walleye dermal sarcoma virus retropepsin

Summary Alignment Sequences Sequence features Distribution Literature Substrates

 

Names
MEROPS Namewalleye dermal sarcoma virus retropepsin
Domain architecture
MEROPS Classification
Classification Clan AA >> Subclan (none) >> Family A2 >> Subfamily D >> A02.063
Holotypewalleye dermal sarcoma virus retropepsin, Uniprot accession O92815 (peptidase unit: 602-704), MERNUM MER0019038
History Identifier created: MEROPS 7.0 (4 April 2005)
Activity
Catalytic typeAspartic
NC-IUBMBNot yet included in IUBMB recommendations.
Proteolytic eventsCutDB database (9 cleavages)
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage patternsv/-/QN/ylScissile bondPvas/Ilv/vrkp/qn (based on 25 cleavages)
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Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 0 1 0 2 0 0 0 0
Pro 0 1 0 0 14 0 3 0
Ala 1 1 0 0 3 1 0 1
Val 4 5 0 0 5 2 11 0
Leu 2 2 0 7 0 5 0 0
Ile 0 0 0 0 0 15 0 0
Met 1 0 0 2 0 1 0 0
Phe 1 1 0 1 0 0 0 0
Tyr 2 1 0 8 0 0 0 1
Trp 0 0 0 0 0 0 0 0
Ser 11 0 0 0 2 0 0 0
Thr 0 0 0 0 1 0 1 2
Cys 1 0 0 0 0 1 0 0
Asn 0 0 11 1 0 0 0 4
Gln 1 5 14 0 0 0 1 11
Asp 0 0 0 0 0 0 0 1
Glu 0 0 0 0 0 0 0 2
Lys 0 2 0 1 0 0 3 2
Arg 0 3 0 2 0 0 5 0
His 1 3 0 1 0 0 1 1