Summary for peptidase A22.005: impas 2 peptidase

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Human EST Mouse EST Inhibitors

 

Names
MEROPS Nameimpas 2 peptidase
Other namesAtSPPL1 (Arabidopsis thaliana), CG17370 protein (Drosophila melanogaster), IMP2, intramembrane protease 2, SPPL3 protein, PSH1, presenilin homologue-1
Domain architecture
MEROPS Classification
Classification Clan AD >> Subclan (none) >> Family A22 >> Subfamily B >> A22.005
Holotypeimpas 2 peptidase (Homo sapiens), Uniprot accession Q8TCT6 (peptidase unit: 1-385), MERNUM MER0019708
History Identifier created: MEROPS 6.0 (30 August 2002)
Activity
Catalytic typeAspartic
NC-IUBMBNot yet included in IUBMB recommendations.
Activity statushuman: putative (Grigorenko et al., 2002)
mouse: putative
Other databases TREEFAMhttp://www.treefam.org/family/TF323842
Human genetics
Gene symbol Locus Megabases Ensembl Entrez gene Gene Cards OMIM
12q24.31 ENSG00000157837 121665 608240
Mouse genetics
Gene symbol Position Megabases Ensembl Entrez gene MGI
Sppl3 5:F ENSMUSG00000029550 74585 MGI:1891433