Summary for peptidase A25.001: gpr peptidase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

 

Names
MEROPS Namegpr peptidase
Other namesgermination protease (bacterial), gpr g.p. (Bacillus megaterium), gpr protease, spore protease
Domain architecture
MEROPS Classification
Classification Clan AE >> Subclan (none) >> Family A25 >> Subfamily (none) >> A25.001
Holotypegpr peptidase (Bacillus megaterium), Uniprot accession P22321 (peptidase unit: 17-371), MERNUM MER0001292
History Identifier created: MEROPS 5.61 (29 October 2001)
Activity
Catalytic typeAspartic
PeplistIncluded in the Peplist with identifier PL00263
NC-IUBMBSubclass 3.4 (Peptidases) >> Sub-subclass 3.4.24 (Metalloendopeptidases) >> Peptidase 3.4.24.78
EnzymologyBRENDA database
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage patternMfy/Kg/ytl/EScissile bondIfv/A/Sqn/E (based on 32 cleavages)
weblogo
Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 0 6 0 0 0 1 0 0
Pro 0 0 0 0 0 0 0 0
Ala 0 1 0 0 0 30 1 0
Val 1 0 0 0 4 0 1 0
Leu 0 0 6 0 1 0 0 0
Ile 0 0 0 0 20 0 0 0
Met 19 0 0 0 0 0 0 0
Phe 9 0 3 0 7 0 0 0
Tyr 3 0 10 0 0 0 0 0
Trp 0 0 0 0 0 0 0 0
Ser 0 0 0 0 0 1 16 0
Thr 0 0 8 0 0 0 2 0
Cys 0 0 0 0 0 0 0 0
Asn 0 0 3 0 0 0 4 0
Gln 0 0 0 0 0 0 7 0
Asp 0 0 0 1 0 0 0 0
Glu 0 0 2 31 0 0 0 32
Lys 0 24 0 0 0 0 0 0
Arg 0 1 0 0 0 0 1 0
His 0 0 0 0 0 0 0 0