Summary for peptidase A26.003: plasminogen activator Pla

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors

 

Names
MEROPS Nameplasminogen activator Pla
Other namescoagulase, endopeptidase pla, Epo peptidase (Erwinia pyrifoliae), Kop peptidase (Klebsiella pneumoniae), Pla g.p. (Yersinia pestis), plasminogen activator (Yersinia pestis)
Domain architecture
MEROPS Classification
Classification Clan AF >> Subclan (none) >> Family A26 >> Subfamily (none) >> A26.003
Holotypeplasminogen activator Pla (Yersinia pestis), Uniprot accession P17811 (peptidase unit: 23-312), MERNUM MER0001779
History Identifier created: MEROPS 5.7 (17 December 2001)
Activity
Catalytic typeAspartic
PeplistIncluded in the Peplist with identifier PL00045
NC-IUBMBSubclass 3.4 (Peptidases) >> Sub-subclass 3.4.23 (Aspartic endopeptidases) >> Peptidase 3.4.23.48
EnzymologyBRENDA database
Proteolytic eventsCutDB database (1 cleavage)
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/-/RScissile bondR/iav/N/- (based on 16 cleavages)
weblogo
Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 0 0 1 0 0 1 1 1
Pro 0 1 0 0 0 0 1 0
Ala 0 0 1 0 0 2 0 0
Val 1 0 0 0 1 2 0 0
Leu 0 0 0 0 0 0 0 0
Ile 0 0 0 0 0 8 0 0
Met 0 0 0 0 1 0 0 0
Phe 0 0 0 0 0 0 0 0
Tyr 0 0 0 0 0 0 0 0
Trp 0 0 0 0 0 0 0 0
Ser 0 1 0 0 0 1 0 0
Thr 0 0 0 0 0 1 0 0
Cys 1 0 0 0 0 1 0 0
Asn 0 0 0 0 0 0 5 0
Gln 0 0 0 0 0 0 0 0
Asp 0 0 0 0 0 0 0 0
Glu 0 0 0 0 0 0 0 1
Lys 0 0 0 0 0 0 0 0
Arg 0 0 0 16 14 0 0 3
His 0 0 0 0 0 0 0 0