Summary for peptidase C01.008: asclepain A

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates Inhibitors

 

Names
MEROPS Nameasclepain A
MEROPS Classification
Classification Clan CA >> Subclan (none) >> Family C1 >> Subfamily A >> C01.008
Holotypeasclepain A (Asclepias syriaca) (peptidase unit: 1-21), MERNUM MER0001985
History Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.
Activity
Catalytic typeCysteine
NC-IUBMBSubclass 3.4 (Peptidases) >> Sub-subclass 3.4.22 (Cysteine endopeptidases) >> Peptidase 3.4.22.7
EnzymologyBRENDA database
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/-/-Scissile bond-/-/-/- (based on 10 cleavages)
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Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 1 2 2 0 2 1 1 2
Pro 0 0 0 0 0 1 1 1
Ala 1 0 0 1 0 0 0 1
Val 0 2 1 0 1 0 1 1
Leu 2 2 0 2 1 2 1 0
Ile 0 0 0 0 0 0 0 0
Met 0 0 0 0 0 0 0 0
Phe 1 1 2 2 1 1 1 0
Tyr 1 0 1 1 1 2 0 1
Trp 0 0 0 0 0 0 0 0
Ser 0 0 0 1 0 0 1 0
Thr 0 0 0 0 1 1 1 0
Cys 0 0 0 0 0 0 0 0
Asn 1 0 1 0 0 0 0 0
Gln 0 1 0 1 0 0 0 0
Asp 0 0 0 0 0 0 0 0
Glu 1 0 2 0 0 1 0 2
Lys 0 0 0 0 0 0 1 1
Arg 1 1 0 1 0 0 1 0
His 0 0 1 0 2 0 0 1