Summary for peptidase C01.010: vignain

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors

 

Names
MEROPS Namevignain
Other namesbean proteinase A, CP56 peptidase (Nicotiana tabacum), CysEP (Ricinus communis), CysP1 (Glycine max), CysP2 (Glycine max), EP8 endopeptidase (Triticum turgidum subsp. durum x Secale cereale), pRP80 (Oryza sativa), endopeptidase A (Hordeum vulgare), NtCP2 peptidase (Nicotiana tabacum), ricinosomal KDEL-containing cysteine peptidase, SEN102 (Hemerocallis sp.), SEN11 (Hemerocallis sp.), SH-EP (Vigna mungo), SlCysEP peptidase (Solanum lycopersicum)
Domain architecture
MEROPS Classification
Classification Clan CA >> Subclan (none) >> Family C1 >> Subfamily A >> C01.010
Holotypevignain (Vigna mungo), Uniprot accession P12412 (peptidase unit: 128-346), MERNUM MER0000650
History Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.
Activity
Catalytic typeCysteine
PeplistIncluded in the Peplist with identifier PL00054
NC-IUBMBNot yet included in IUBMB recommendations.
PhysiologyMobilises protein reserves in plant seed germination.
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/l/-Scissile bondQ/Q/-/Dp (based on 80 cleavages)
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Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 1 1 1 2 3 0 0 1
Pro 6 8 6 3 3 7 7 10
Ala 1 1 1 2 3 3 2 2
Val 3 2 9 3 1 9 2 3
Leu 5 5 30 6 4 1 3 2
Ile 1 0 2 2 1 1 2 0
Met 2 2 4 3 1 2 2 0
Phe 2 1 5 3 2 1 4 1
Tyr 0 1 1 3 2 1 1 2
Trp 0 1 1 1 1 1 0 0
Ser 5 6 2 9 4 4 4 3
Thr 0 2 1 4 1 2 1 0
Cys 0 0 1 1 0 0 0 0
Asn 0 0 1 1 1 0 0 1
Gln 5 1 6 6 45 44 5 8
Asp 2 1 1 2 1 0 1 39
Glu 3 5 1 2 2 2 2 2
Lys 3 3 3 3 5 1 3 3
Arg 1 0 2 22 0 0 0 0
His 1 1 2 2 0 1 2 3