Summary for peptidase C01.024: endopeptidase-B (Hordeum-type)

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors

 

Names
MEROPS Nameendopeptidase-B (Hordeum-type)
Other namesallergen Amb a 11 (Ambrosia artemisiifolia), EP-B1 (Hordeum vulgare), EP-B2 (Hordeum vulgare), EP-B4 (Hordeum vulgare), gliadain (Triticum aestivum), OsEP3A endopeptidase (Oryza sativa), pREP1 endopeptidase (Oryza sativa), Rep1 endopeptidase (Oryza sativa)
Domain architecture
MEROPS Classification
Classification Clan CA >> Subclan (none) >> Family C1 >> Subfamily A >> C01.024
Holotypeendopeptidase-B (Hordeum-type) (Hordeum vulgare), Uniprot accession P25250 (peptidase unit: 134-355), MERNUM MER0000660
History Identifier created: MEROPS 5.0 (17 April 2000)
Activity
Catalytic typeCysteine
NC-IUBMBNot yet included in IUBMB recommendations.
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage patternpq/qp/lp/qrScissile bondQ/P/fq/dpq (based on 70 cleavages)
weblogo
Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 2 3 0 4 4 0 0 0
Pro 12 7 23 0 0 46 3 16
Ala 1 0 0 1 1 1 3 0
Val 1 0 2 1 0 1 1 1
Leu 3 3 23 3 0 1 3 4
Ile 2 3 1 2 3 1 1 0
Met 0 0 4 1 1 0 0 0
Phe 1 4 6 1 2 1 12 0
Tyr 2 3 2 2 1 1 6 2
Trp 1 0 2 1 0 0 0 1
Ser 1 1 0 2 2 4 1 0
Thr 2 0 1 1 1 1 1 1
Cys 1 0 0 1 0 0 0 0
Asn 0 0 0 1 1 0 0 0
Gln 12 13 5 31 50 11 8 10
Asp 0 0 0 1 0 0 0 26
Glu 0 3 1 2 1 0 1 3
Lys 0 0 0 1 1 0 0 1
Arg 1 2 0 11 0 0 0 1
His 0 0 0 3 0 0 1 1