Summary for peptidase C01.026: ananain

Summary Alignment Sequences Sequence features Distribution Literature Substrates Inhibitors

 

Names
MEROPS Nameananain
Domain architecture
MEROPS Classification
Classification Clan CA >> Subclan (none) >> Family C1 >> Subfamily A >> C01.026
Holotypeananain (Ananas comosus), Uniprot accession P80884 (peptidase unit: 123-337), MERNUM MER0003651
History Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.
Activity
Catalytic typeCysteine
PeplistIncluded in the Peplist with identifier PL00058
NC-IUBMBSubclass 3.4 (Peptidases) >> Sub-subclass 3.4.22 (Cysteine endopeptidases) >> Peptidase 3.4.22.31
EnzymologyBRENDA database
Pharmaceutical relevanceBurn debridement (patent).
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/-/clmqrScissile bondknq/-/-/- (based on 17 cleavages)
weblogo
Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 0 1 0 0 0 0 0 0
Pro 0 0 0 0 0 0 0 0
Ala 0 0 0 0 0 0 0 0
Val 0 0 1 0 0 0 0 0
Leu 0 0 0 3 0 0 0 0
Ile 0 0 0 0 0 0 0 0
Met 0 0 0 3 0 0 0 0
Phe 0 1 3 0 0 0 0 0
Tyr 0 0 0 0 0 0 0 0
Trp 0 0 0 0 0 0 0 0
Ser 0 0 0 0 0 0 0 0
Thr 0 0 0 0 0 0 0 0
Cys 0 0 0 3 0 0 0 0
Asn 0 0 0 0 4 0 0 0
Gln 0 0 0 3 4 0 0 0
Asp 0 0 0 0 0 0 0 0
Glu 0 0 0 0 0 0 0 0
Lys 0 0 0 0 4 0 0 0
Arg 0 0 1 3 0 0 0 0
His 0 0 0 0 0 0 0 0