Summary for peptidase C13.001: legumain (plant beta form)

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates Inhibitors

 

Names
MEROPS Namelegumain (plant beta form)
Other namesasparaginyl endopeptidase, bean endopeptidase, citvac, nucellain, vacuolar processing enzyme, vicilin peptidohydrolase, VmPE-1, VPE, betaVPE
Domain architecture
MEROPS Classification
Classification Clan CD >> Subclan (none) >> Family C13 >> Subfamily (none) >> C13.001
Holotypelegumain (plant beta form) (Canavalia ensiformis), Uniprot accession P49046 (peptidase unit: 36-312), MERNUM MER0000845
History Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.
Activity
Catalytic typeCysteine
PeplistIncluded in the Peplist with identifier PL00096
NC-IUBMBSubclass 3.4 (Peptidases) >> Sub-subclass 3.4.22 (Cysteine endopeptidases) >> Peptidase 3.4.22.34
EnzymologyBRENDA database
PhysiologyPlant seed storage protein maturation.
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/adev/NScissile bonds/il/-/- (based on 15 cleavages)
weblogo
Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 0 0 0 0 2 1 3 0
Pro 2 0 0 0 1 1 0 0
Ala 1 2 5 0 0 0 0 0
Val 0 0 2 0 1 1 2 1
Leu 0 0 0 0 0 3 1 0
Ile 1 1 0 0 0 4 0 3
Met 0 0 0 0 0 0 0 1
Phe 0 2 0 0 0 0 1 0
Tyr 0 0 0 0 0 0 0 0
Trp 0 0 0 0 0 0 0 1
Ser 1 3 0 0 4 0 0 2
Thr 1 2 0 0 2 0 0 0
Cys 0 0 0 0 0 0 0 0
Asn 0 0 0 15 0 0 1 2
Gln 0 2 0 0 0 0 0 0
Asp 2 0 4 0 1 1 1 0
Glu 2 1 2 0 0 0 2 2
Lys 2 1 0 0 0 0 1 0
Arg 1 0 1 0 0 0 0 0
His 0 0 0 0 1 1 0 0