Summary for peptidase C16.001: murine hepatitis coronavirus papain-like peptidase 1

Summary Alignment Sequences Sequence features Distribution Literature Substrates


MEROPS Namemurine hepatitis coronavirus papain-like peptidase 1
Other namesbovine coronavirus papain-like endopeptidase 1, leader endopeptidase, MHV papain-like endopeptidase 1, mouse hepatitis coronavirus papain-like endopeptidase 1, PL1-PRO
Domain architecture
MEROPS Classification
Classification Clan CA >> Subclan (none) >> Family C16 >> Subfamily A >> C16.001
Holotypemurine hepatitis coronavirus papain-like peptidase 1 (murine hepatitis virus), Uniprot accession P19751 (peptidase unit: 1083-1332), MERNUM MER0000859
History Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.
Catalytic typeCysteine
PeplistIncluded in the Peplist with identifier PL00107
NC-IUBMBNot yet included in IUBMB recommendations.
Proteolytic eventsCutDB database (2 cleavages)
PhysiologyViral polyprotein processing in replication.