Summary for peptidase C28.001: foot-and-mouth disease virus L-peptidase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors


MEROPS Namefoot-and-mouth disease virus L-peptidase
Other namesfoot-and-mouth disease virus L-proteinase, leader proteinase, Lb proteinase, NSp20a, FMDV L-peptidase
Domain architecture
MEROPS Classification
Classification Clan CA >> Subclan (none) >> Family C28 >> Subfamily (none) >> C28.001
Holotypefoot-and-mouth disease virus L-peptidase, Uniprot accession P03307 (peptidase unit: 1-201), MERNUM MER0002022
History Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.
Catalytic typeCysteine
PeplistIncluded in the Peplist with identifier PL00114
NC-IUBMBSubclass 3.4 (Peptidases) >> Sub-subclass 3.4.22 (Cysteine endopeptidases) >> Peptidase
EnzymologyBRENDA database
Proteolytic eventsCutDB database (4 cleavages)
PhysiologyViral polyprotein processing by this cattle pathogen. Degradation of host cell eIF-4G.