Summary for peptidase C54.002: autophagin-2

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Human EST Mouse EST Substrates

 

Names
MEROPS Nameautophagin-2
Other namesATG4A g.p. (Homo sapiens), AUTL2 putative peptidase, HsApg4A protein, Mername-AA006 peptidase
Domain architecture
MEROPS Classification
Classification Clan CA >> Subclan (none) >> Family C54 >> Subfamily (none) >> C54.002
Holotypeautophagin-2 (Homo sapiens), Uniprot accession Q8WYN0 (peptidase unit: 31-343), MERNUM MER0013564
History Identifier created: MEROPS 5.3 (4 December 2000)
Activity
Catalytic typeCysteine
NC-IUBMBNot yet included in IUBMB recommendations.
Activity statushuman: active (Scherz-Shouval et al., 2002)
mouse: putative
Pathways KEGGRegulation of autophagy
Other databases TREEFAMhttp://www.treefam.org/family/TF314847
Human genetics
Gene symbol Locus Megabases Ensembl Entrez gene Gene Cards OMIM
ATG4A Xq22.1-q22.3 ENSG00000101844 115201 APG4A 300663
Mouse genetics
Gene symbol Position Megabases Ensembl Entrez gene MGI
Atg4a X:F1 ENSMUSG00000079418 666468 MGI:2147903