Summary for peptidase C54.004: autophagin-3

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Human EST Mouse EST Substrates Inhibitors

 

Names
MEROPS Nameautophagin-3
Other namesATG4C peptidase, AUTL1 g.p. (Homo sapiens), Mername-AA037 peptidase, PLACE1002319 peptidase
Domain architecture
MEROPS Classification
Classification Clan CA >> Subclan (none) >> Family C54 >> Subfamily (none) >> C54.004
Holotypeautophagin-3 (Homo sapiens), Uniprot accession Q96DT6 (peptidase unit: 43-407), MERNUM MER0014316
History Identifier created: MEROPS 5.5 (16 June 2001)
Activity
Catalytic typeCysteine
NC-IUBMBNot yet included in IUBMB recommendations.
Activity statushuman: active (Marino et al., 2003)
mouse: active (by similarity to human)
Pathways KEGGRegulation of autophagy
Other databases TREEFAMhttp://www.treefam.org/family/TF314847
Human genetics
Gene symbol Locus Megabases Ensembl Entrez gene Gene Cards OMIM
ATG4C 1p31.3 ENSG00000125703 84938 APG4C 611339
Mouse genetics
Gene symbol Position Megabases Ensembl Entrez gene MGI
Atg4c 4:C6 ENSMUSG00000028550 242557 MGI:2651854