Summary for peptidase C54.004: autophagin-3

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Human EST Mouse EST Substrates Inhibitors


MEROPS Nameautophagin-3
Other namesATG4C peptidase, AUTL1 g.p. (Homo sapiens), Mername-AA037 peptidase, PLACE1002319 peptidase
Domain architecture
MEROPS Classification
Classification Clan CA >> Subclan (none) >> Family C54 >> Subfamily (none) >> C54.004
Holotypeautophagin-3 (Homo sapiens), Uniprot accession Q96DT6 (peptidase unit: 43-407), MERNUM MER0014316
History Identifier created: MEROPS 5.5 (16 June 2001)
Catalytic typeCysteine
NC-IUBMBNot yet included in IUBMB recommendations.
Activity statushuman: active (Marino et al., 2003)
mouse: active (by similarity to human)
Pathways KEGGRegulation of autophagy
Other databases TREEFAM
Human genetics
Gene symbol Locus Megabases Ensembl Entrez gene Gene Cards OMIM
ATG4C 1p31.3 ENSG00000125703 84938 APG4C 611339
Mouse genetics
Gene symbol Position Megabases Ensembl Entrez gene MGI
Atg4c 4:C6 ENSMUSG00000028550 242557 MGI:2651854