Summary for peptidase C55.001: YopJ protein

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates


MEROPS NameYopJ protein
Other namesYersinia outer protein J, YopJ g.p. (Yersinia sp.), YopP g.p.(Yersina enterocolitica)
Domain architecture
MEROPS Classification
Classification Clan CE >> Subclan (none) >> Family C55 >> Subfamily (none) >> C55.001
HolotypeYopJ protein (Yersinia pseudotuberculosis), Uniprot accession P31498 (peptidase unit: 1-264), MERNUM MER0005912
History Identifier created: MEROPS 5.4 (23 March 2001)
Catalytic typeCysteine
PeplistIncluded in the Peplist with identifier PL00120
NC-IUBMBNot yet included in IUBMB recommendations.
PhysiologyA bacterial virulence effector, mediating inhibition of the mitogen-activated protein kinase (MAPK) and nuclear factor kappaB (NF-kappaB) signaling in animal cells, and inducing localized cell death in plants (Orth et al., 2000).