Summary for peptidase C60.001: sortase A (Staphylococcus-type)

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors

 

Names
MEROPS Namesortase A (Staphylococcus-type)
Other namesSrtA g.p. (Staphylococcus aureus)
Domain architecture
MEROPS Classification
Classification Clan CL >> Subclan (none) >> Family C60 >> Subfamily A >> C60.001
Holotypesortase A (Staphylococcus-type) (Staphylococcus aureus) (peptidase unit: 1-206), MERNUM MER0018290
History Identifier created: MEROPS 6.1 (10 January 2003)
Activity
Catalytic typeCysteine
PeplistIncluded in the Peplist with identifier PL00122
NC-IUBMBSubclass 3.4 (Peptidases) >> Sub-subclass 3.4.22 (Cysteine endopeptidases) >> Peptidase 3.4.22.70
EnzymologyBRENDA database
Proteolytic eventsCutDB database (1 cleavage)
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage patternL/P/kdeq/TScissile bondG/e/est/s (based on 16 cleavages)
weblogo
Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 0 0 0 0 16 2 0 0
Pro 0 16 0 0 0 0 0 0
Ala 0 0 1 2 0 1 1 1
Val 0 0 0 0 0 0 0 0
Leu 15 0 0 0 0 2 0 0
Ile 0 0 0 0 0 0 0 3
Met 0 0 0 0 0 2 0 1
Phe 0 0 0 0 0 0 0 0
Tyr 0 0 0 0 0 0 0 0
Trp 0 0 0 0 0 0 0 0
Ser 1 0 0 0 0 0 3 5
Thr 0 0 0 14 0 1 3 1
Cys 0 0 0 0 0 0 0 0
Asn 0 0 0 0 0 1 2 1
Gln 0 0 2 0 0 0 0 1
Asp 0 0 3 0 0 2 1 0
Glu 0 0 3 0 0 5 5 2
Lys 0 0 7 0 0 0 1 0
Arg 0 0 0 0 0 0 0 0
His 0 0 0 0 0 0 0 1