Summary for peptidase C86.001: ataxin-3

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Human EST Mouse EST Substrates Inhibitors

 

Names
MEROPS Nameataxin-3
Other namesATXN3 g.p. (Homo sapiens), Josephin, Machado-Joseph disease protein, MJD protein
Domain architecture
MEROPS Classification
Classification Clan CA >> Subclan (none) >> Family C86 >> Subfamily (none) >> C86.001
Holotypeataxin-3 (Homo sapiens), Uniprot accession P54252 (peptidase unit: 1-180), MERNUM MER0099998
History Identifier created: MEROPS 8.00A (14 February 2008)
Activity
Catalytic typeCysteine
NC-IUBMBNot yet included in IUBMB recommendations.
Other databases TREEFAMhttp://www.treefam.org/family/TF314228
Human genetics
Gene symbol Locus Megabases Ensembl Entrez gene Gene Cards OMIM
ATXN3 14q24.3-q32.2 ENSG00000066427 4287 607047
Mouse genetics
Gene symbol Position Megabases Ensembl Entrez gene MGI
Atxn3 12:E ENSMUSG00000021189 110616 MGI:1099442