Summary for peptidase G01.002: aspergilloglutamic peptidase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors

 

Names
MEROPS Nameaspergilloglutamic peptidase
Other namesaspergillopepsin II, aspergillopepsin B, Aspergillus niger var. macrosporus aspartic proteinase, PepB g.p. (Aspergillus niger), proctase A, proteinase A
Domain architecture
MEROPS Classification
Classification Clan GA >> Subclan (none) >> Family G1 >> Subfamily (none) >> G01.002
Holotypeaspergilloglutamic peptidase (Aspergillus niger), Uniprot accession P24665 (peptidase unit: 64-282), MERNUM MER0001321
History Identifier created: MEROPS 6.6 (29 March 2004)
Activity
Catalytic typeGlutamic
PeplistIncluded in the Peplist with identifier PL00037
NC-IUBMBSubclass 3.4 (Peptidases) >> Sub-subclass 3.4.23 (Aspartic endopeptidases) >> Peptidase 3.4.23.19
EnzymologyBRENDA database
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/-/-Scissile bond-/-/-/- (based on 68 cleavages)
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Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 8 3 0 0 6 2 0 0
Pro 2 6 2 0 1 5 6 0
Ala 11 4 5 1 8 6 8 9
Val 6 4 10 1 5 2 8 3
Leu 4 3 6 4 3 7 4 2
Ile 0 1 0 0 3 2 1 2
Met 1 1 2 4 1 0 3 1
Phe 2 4 6 5 2 3 3 6
Tyr 2 4 5 9 1 1 3 2
Trp 0 0 2 0 0 1 0 2
Ser 6 3 4 1 11 5 5 12
Thr 2 3 6 0 6 6 6 3
Cys 2 5 2 0 1 0 2 1
Asn 2 2 1 9 3 5 2 2
Gln 3 5 2 7 1 3 4 3
Asp 4 1 1 5 1 2 0 3
Glu 3 3 1 8 5 2 3 2
Lys 4 5 8 8 5 5 6 3
Arg 0 8 3 1 5 5 3 5
His 2 3 2 5 0 6 1 4