Summary for peptidase M01.005: alanyl aminopeptidase (bacterial-type)

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors Pharma

 

Names
MEROPS Namealanyl aminopeptidase (bacterial-type)
Other namesaminopeptidase M1 (Arabidopsis thaliana), APM1 (Arabidopsis thaliana), aminopeptidase N (Escherichia coli), AtMPA-1, pepN g.p. (Escherichia coli), peptidase N
Domain architecture
MEROPS Classification
Classification Clan MA >> Subclan MA(E) >> Family M1 >> Subfamily (none) >> M01.005
Holotypealanyl aminopeptidase (bacterial-type) (Escherichia coli), Uniprot accession P04825 (peptidase unit: 212-421), MERNUM MER0001001
History Identifier created: MEROPS 3.02 (25 June 1998)
Activity
Catalytic typeMetallo
NC-IUBMBNot yet included in IUBMB recommendations.
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/agl/-/aScissile bond-/-/-/- (based on 17 cleavages)
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Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 0 2 1 0 1 0 0 0
Pro 0 0 0 1 0 0 0 0
Ala 0 2 2 4 0 0 0 0
Val 0 0 1 0 0 0 0 0
Leu 1 2 0 2 0 0 0 0
Ile 0 0 0 0 0 0 0 0
Met 0 0 0 0 0 0 0 0
Phe 0 0 0 2 0 0 0 0
Tyr 0 0 0 3 0 0 0 0
Trp 0 0 0 0 0 0 0 0
Ser 0 0 0 0 0 0 0 0
Thr 1 0 0 1 0 0 0 0
Cys 0 0 0 1 0 0 0 0
Asn 0 0 1 0 1 0 0 0
Gln 0 0 0 0 0 0 0 0
Asp 0 0 0 0 0 0 0 0
Glu 0 0 0 0 0 0 0 0
Lys 0 0 0 0 0 0 0 0
Arg 0 0 1 3 0 0 0 0
His 0 0 0 0 0 0 0 0