Summary for peptidase M01.022: arginyl aminopeptidase-like 1

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Human EST Mouse EST Substrates

 

Names
MEROPS Namearginyl aminopeptidase-like 1
Other namesaminopeptidase B-like, APB-L, Mername-AA050 peptidase, RNPEP-like protein1, RNPEPL1
Domain architecture
MEROPS Classification
Classification Clan MA >> Subclan MA(E) >> Family M1 >> Subfamily (none) >> M01.022
Holotypearginyl aminopeptidase-like 1 (Homo sapiens), Uniprot accession Q9HAU8 (peptidase unit: 35-280), MERNUM MER0012271
History Identifier created: MEROPS 5.3 (4 December 2000)
Activity
Catalytic typeMetallo
NC-IUBMBSubclass 3.4 (Peptidases) >> Sub-subclass 3.4.11 (Aminopeptidases) >> Peptidase 3.4.11.1
EnzymologyBRENDA database
Activity statushuman: putative
mouse: putative
Other databases TREEFAMhttp://www.treefam.org/family/TF300758
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/-/-Scissile bond-/-/-/- (based on 14 cleavages)
weblogo
Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 0 0 0 0 0 0 0 0
Pro 0 0 0 0 0 0 0 0
Ala 0 0 0 1 0 0 0 0
Val 0 0 0 0 0 0 0 0
Leu 0 0 0 1 0 0 0 0
Ile 0 0 0 1 0 0 0 0
Met 0 0 0 1 0 0 0 0
Phe 0 0 0 1 0 0 0 0
Tyr 0 0 0 1 0 0 0 0
Trp 0 0 0 1 0 0 0 0
Ser 0 0 0 1 0 0 0 0
Thr 0 0 0 0 0 0 0 0
Cys 0 0 0 0 0 0 0 0
Asn 0 0 0 1 0 0 0 0
Gln 0 0 0 1 0 0 0 0
Asp 0 0 0 0 0 0 0 0
Glu 0 0 0 0 0 0 0 0
Lys 0 0 0 1 0 0 0 0
Arg 0 0 0 1 0 0 0 0
His 0 0 0 1 0 0 0 0
Human genetics
Gene symbol Locus Megabases Ensembl Entrez gene Gene Cards OMIM
RNPEPL1 2q37.3 ENSG00000142327 57140 RNPEPL1 605287
Mouse genetics
Gene symbol Position Megabases Ensembl Entrez gene MGI
Rnpepl1 1:D ENSMUSG00000026269 108657 MGI:1914170