Summary for peptidase M01.026: aminopeptidase Q

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Human EST Mouse EST Substrates Inhibitors

 

Names
MEROPS Nameaminopeptidase Q
Other nameslaeverin, Mername-AA105 peptidase, Mername-AA009 protein, Mername-AA120 peptidase, Taqpep
Domain architecture
MEROPS Classification
Classification Clan MA >> Subclan MA(E) >> Family M1 >> Subfamily (none) >> M01.026
Holotypeaminopeptidase Q (Homo sapiens), Uniprot accession Q6Q4G3 (peptidase unit: 324-545), MERNUM MER0052595
History Identifier created: MEROPS 5.61 (29 October 2001)
Activity
Catalytic typeMetallo
NC-IUBMBNot yet included in IUBMB recommendations.
Proteolytic eventsCutDB database (3 cleavages)
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/-/-Scissile bond-/-/-/- (based on 17 cleavages)
weblogo
Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 0 0 0 2 2 1 0 1
Pro 0 0 0 0 0 1 1 0
Ala 0 0 0 1 1 1 0 0
Val 0 0 0 0 1 0 0 0
Leu 0 0 0 1 0 1 1 2
Ile 0 0 0 0 0 0 1 0
Met 0 0 0 1 0 0 0 0
Phe 0 0 0 1 1 1 1 1
Tyr 0 0 0 2 0 2 1 0
Trp 0 0 0 0 1 1 0 0
Ser 0 0 0 0 0 0 1 1
Thr 0 0 0 0 0 0 0 0
Cys 0 0 0 1 0 0 0 0
Asn 0 0 0 1 1 1 1 0
Gln 0 0 0 1 0 0 1 1
Asp 0 0 0 0 0 0 0 0
Glu 0 0 0 0 0 0 0 0
Lys 0 0 0 4 1 0 0 0
Arg 0 0 0 2 1 0 1 2
His 0 0 0 0 0 0 0 1
Human genetics
Gene symbol Locus Megabases Ensembl Entrez gene Gene Cards OMIM
5q23.1 ENSG00000172901 206338 610046