Summary for peptidase M02.002: peptidyl-dipeptidase Acer

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates Inhibitors

 

Names
MEROPS Namepeptidyl-dipeptidase Acer
Other namesAcer protein (Drosophila melanogaster), RACE
Domain architecture
MEROPS Classification
Classification Clan MA >> Subclan MA(E) >> Family M2 >> Subfamily (none) >> M02.002
Holotypepeptidyl-dipeptidase Acer (Drosophila melanogaster), Uniprot accession Q9VLJ6 (peptidase unit: 26-630), MERNUM MER0002827
History Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.
Activity
Catalytic typeMetallo
PeplistIncluded in the Peplist with identifier PL00133
NC-IUBMBSubclass 3.4 (Peptidases) >> Sub-subclass 3.4.15 (Peptidyl-dipeptidases) >> Peptidase 3.4.15.1
EnzymologyBRENDA database
Proteolytic eventsCutDB database (1 cleavage)
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage patterngq/fy/sfgt/gpScissile bondfl/rlm/-/- (based on 11 cleavages)
weblogo
Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 4 0 2 5 1 0 0 0
Pro 0 1 0 4 0 0 0 0
Ala 0 0 0 0 0 0 0 0
Val 0 0 0 0 0 0 0 0
Leu 0 0 0 0 3 3 0 0
Ile 0 0 0 0 0 0 0 0
Met 0 0 0 0 0 2 1 0
Phe 0 5 2 1 5 1 0 0
Tyr 0 3 0 0 1 0 0 0
Trp 0 0 0 0 0 0 0 0
Ser 0 0 3 0 0 0 0 0
Thr 0 0 2 0 0 0 0 0
Cys 0 0 0 0 0 0 0 0
Asn 1 0 0 1 0 0 0 0
Gln 2 1 0 0 0 0 0 0
Asp 0 0 0 0 0 0 0 0
Glu 0 0 0 0 0 0 0 0
Lys 0 0 0 0 0 0 0 0
Arg 0 0 0 0 0 4 0 0
His 0 0 0 0 1 1 0 0