Summary for peptidase M03.007: oligopeptidase F

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors

 

Names
MEROPS Nameoligopeptidase F
Other namesPepF1 g.p. (Lactococcus lactis), Lactococcus endopeptidase I, LEP I, oligopeptidase PepB (Streptococcus), PZ-peptidase (Bacillus licheniformis), Pz-peptidase B (Geobacillus sp.), yjbG g.p. (Bacillus subtilis)
Domain architecture
MEROPS Classification
Classification Clan MA >> Subclan MA(E) >> Family M3 >> Subfamily B >> M03.007
Holotypeoligopeptidase F (Lactococcus lactis), Uniprot accession Q9CEV7 (peptidase unit: 290-571), MERNUM MER0001163
History Identifier created: Incorrectly cited in Handbook
Activity
Catalytic typeMetallo
PeplistIncluded in the Peplist with identifier PL00142
NC-IUBMBNot yet included in IUBMB recommendations.
Proteolytic eventsCutDB database (3 cleavages)
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/-/lScissile bondg/p/l/- (based on 24 cleavages)
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Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 0 4 1 1 9 1 1 4
Pro 3 1 7 1 0 11 2 0
Ala 0 0 1 0 0 0 1 0
Val 1 1 0 1 1 0 1 1
Leu 2 1 2 9 0 2 7 1
Ile 0 0 0 0 0 1 0 1
Met 1 1 0 1 0 0 1 1
Phe 1 1 1 4 2 0 3 0
Tyr 1 2 2 1 2 1 2 0
Trp 0 0 1 1 0 1 1 0
Ser 2 1 2 1 1 0 1 0
Thr 0 0 0 0 0 0 0 0
Cys 0 0 0 0 0 0 0 0
Asn 1 0 0 0 2 1 0 2
Gln 1 3 2 0 1 1 0 0
Asp 0 0 0 0 0 0 0 0
Glu 0 1 1 2 2 0 1 1
Lys 0 1 0 0 1 2 0 1
Arg 1 2 2 1 2 1 1 3
His 1 0 1 1 1 1 0 0