Summary for peptidase M10.051: serralysin

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors


MEROPS Nameserralysin
Other namesarazyme (Serratia proteomaculans), Serratia marcescens extracellular proteinase
Domain architecture
MEROPS Classification
Classification Clan MA >> Subclan MA(M) >> Family M10 >> Subfamily B >> M10.051
Holotypeserralysin (Serratia marcescens), Uniprot accession P23694 (peptidase unit: 69-243), MERNUM MER0001096
History Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.
Catalytic typeMetallo
PeplistIncluded in the Peplist with identifier PL00170
NC-IUBMBSubclass 3.4 (Peptidases) >> Sub-subclass 3.4.24 (Metalloendopeptidases) >> Peptidase
EnzymologyBRENDA database
Proteolytic eventsCutDB database (2 cleavages)
PhysiologyBacterial nutrition. Considered virulence factor. Causes shedding of host cell surface proteins.