Summary for peptidase M12.137: BHRa hemorrhagin (Bitis arietans)

Summary Distribution Literature Substrates Inhibitors

 

Names
MEROPS NameBHRa hemorrhagin (Bitis arietans)
MEROPS Classification
Classification Clan MA >> Subclan MA(M) >> Family M12 >> Subfamily B >> M12.137
History Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.
Activity
Catalytic typeMetallo
NC-IUBMBNot yet included in IUBMB recommendations.
Proteolytic eventsCutDB database (1 cleavage)
PhysiologyLikely role in snake venom toxicity.
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/-/rScissile bondlf/-/-/- (based on 14 cleavages)
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Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 1 1 1 2 1 1 1 1
Pro 0 1 0 1 0 0 0 2
Ala 0 1 0 2 0 0 0 1
Val 0 3 0 0 0 2 0 2
Leu 3 0 1 1 4 1 3 0
Ile 0 1 0 0 0 0 0 0
Met 0 0 0 0 0 0 0 0
Phe 0 0 2 1 3 1 0 1
Tyr 1 0 0 2 0 3 1 0
Trp 0 0 1 0 0 0 0 0
Ser 0 1 1 0 0 0 1 0
Thr 0 0 0 0 0 0 1 1
Cys 0 0 0 0 0 0 0 0
Asn 1 0 0 0 0 0 0 0
Gln 0 1 0 0 0 0 0 0
Asp 0 0 0 0 0 0 0 0
Glu 2 1 2 0 1 0 1 0
Lys 0 0 0 0 0 0 0 0
Arg 0 1 1 4 0 1 1 0
His 1 0 2 1 0 1 0 1