Summary for peptidase M12.147: atroxase

Summary Alignment Sequences Sequence features Distribution Literature Substrates


MEROPS Nameatroxase
Other namesCrotalus atrox venom non-hemorrhagic endopeptidase
Domain architecture
MEROPS Classification
Classification Clan MA >> Subclan MA(M) >> Family M12 >> Subfamily B >> M12.147
Holotypeatroxase (Crotalus atrox), Uniprot accession Q91401 (peptidase unit: 3-199), MERNUM MER0001989
History Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.
Catalytic typeMetallo
PeplistIncluded in the Peplist with identifier PL00188
NC-IUBMBSubclass 3.4 (Peptidases) >> Sub-subclass 3.4.24 (Metalloendopeptidases) >> Peptidase
EnzymologyBRENDA database
PhysiologyLikely role in snake venom toxicity through fibrinolytic activity.
Pharmaceutical relevancePotential anticoagulant or thrombolytic agent.