Summary for peptidase M13.004: oligopeptidase O1

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates Inhibitors

 

Names
MEROPS Nameoligopeptidase O1
Other namesendopeptidase II (Lactococcus), endopeptidase O, pepO, pepO1 g.p. (Lactobacillus lactis)
Domain architecture
MEROPS Classification
Classification Clan MA >> Subclan MA(E) >> Family M13 >> Subfamily (none) >> M13.004
Holotypeoligopeptidase O1 (Lactococcus lactis), Uniprot accession Q02VB0 (peptidase unit: 1-626), MERNUM MER0001058
History Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.
Activity
Catalytic typeMetallo
PeplistIncluded in the Peplist with identifier PL00203
NC-IUBMBNot yet included in IUBMB recommendations.
BiotechnologyPotential use in enhancement of flavor of cheese.
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/-/pScissile bond-/-/-/- (based on 10 cleavages)
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Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 1 1 1 0 1 2 2 0
Pro 2 2 3 3 0 1 2 2
Ala 0 0 2 2 0 0 0 0
Val 1 0 1 2 2 2 2 1
Leu 1 1 0 2 2 1 0 0
Ile 0 0 0 1 2 1 0 0
Met 0 0 0 0 0 0 0 0
Phe 0 2 1 0 2 0 0 1
Tyr 1 0 0 0 0 0 1 0
Trp 0 0 0 0 0 0 0 0
Ser 0 0 0 0 0 0 0 0
Thr 0 0 0 0 0 0 0 0
Cys 0 0 0 0 0 0 0 0
Asn 0 0 0 0 0 0 0 0
Gln 1 1 0 0 0 0 0 0
Asp 0 0 0 0 0 0 0 0
Glu 1 1 1 0 0 0 0 0
Lys 0 0 0 0 0 0 0 0
Arg 0 0 0 0 1 1 0 1
His 0 0 1 0 0 0 0 0