Summary for peptidase M13.011: MEP peptidase (nematode)

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

 

Names
MEROPS NameMEP peptidase (nematode)
Other namesAce-MEP-6, MEP endopeptidase (Ancylostoma caninum, Haemonchus contortus), MEP-6 endopeptidase (Ancylostoma caninum)
Domain architecture
MEROPS Classification
Classification Clan MA >> Subclan MA(E) >> Family M13 >> Subfamily (none) >> M13.011
HolotypeMEP peptidase (nematode) (Ancylostoma caninum) (peptidase unit: 118-867), MERNUM MER0015175
History Identifier created: MEROPS 6.5 (22 December 2003)
Activity
Catalytic typeMetallo
NC-IUBMBNot yet included in IUBMB recommendations.
Proteolytic eventsCutDB database (56 cleavages)
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/vl/-Scissile bond-/lv/-/- (based on 57 cleavages)
weblogo
Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 2 5 6 2 4 5 7 5
Pro 1 0 2 1 1 2 4 3
Ala 13 8 8 11 9 9 6 8
Val 4 8 15 0 2 11 3 5
Leu 5 5 10 8 9 11 9 1
Ile 1 0 0 0 0 0 0 0
Met 0 0 0 0 0 2 0 0
Phe 2 6 1 0 2 0 0 4
Tyr 3 0 0 1 0 1 0 1
Trp 0 0 0 0 0 1 2 0
Ser 3 2 3 6 6 1 3 3
Thr 3 0 3 2 0 1 3 4
Cys 0 0 0 1 0 0 0 0
Asn 3 3 1 4 4 0 3 4
Gln 2 2 1 0 2 0 1 0
Asp 3 3 1 8 6 9 8 3
Glu 2 0 0 1 0 0 1 3
Lys 6 4 4 7 2 1 4 6
Arg 0 1 0 1 3 0 0 1
His 2 8 2 4 7 3 3 6