Summary for peptidase M14.002: carboxypeptidase A2

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Human EST Mouse EST Substrates Inhibitors Pharma


MEROPS Namecarboxypeptidase A2
Other namesCPA2 g.p. (Homo sapiens)
Domain architecture
MEROPS Classification
Classification Clan MC >> Subclan (none) >> Family M14 >> Subfamily A >> M14.002
Holotypecarboxypeptidase A2 (Homo sapiens), Uniprot accession P48052 (peptidase unit: 115-419), MERNUM MER0001608
History Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.
Catalytic typeMetallo
PeplistIncluded in the Peplist with identifier PL00207
NC-IUBMBSubclass 3.4 (Peptidases) >> Sub-subclass 3.4.17 (Metallocarboxypeptidases) >> Peptidase
EnzymologyBRENDA database
Activity statushuman: active (Auld, 2004)
mouse: active (by similarity)
Pathways KEGGPancreatic secretion
KEGGProtein digestion and absorption
Other databases WIKIPEDIA
Human genetics
Gene symbol Locus Megabases Ensembl Entrez gene Gene Cards OMIM
CPA2 7q32 ENSG00000158516 1358 CPA2 600688
Mouse genetics
Gene symbol Position Megabases Ensembl Entrez gene MGI
Cpa2 6:A3.3 ENSMUSG00000071553 232680 MGI:3617840