Summary for peptidase M20.003: peptidase T

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

 

Names
MEROPS Namepeptidase T
Other namesPepT g.p. (Bacillis subtilis, Lactococcus spp., Salmonella spp.), tripeptidase
Domain architecture
MEROPS Classification
Classification Clan MH >> Subclan (none) >> Family M20 >> Subfamily B >> M20.003
Holotypepeptidase T (Escherichia coli), Uniprot accession P29745 (peptidase unit: 13-408), MERNUM MER0001421
History Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.
Activity
Catalytic typeMetallo
PeplistIncluded in the Peplist with identifier PL00230
NC-IUBMBNot yet included in IUBMB recommendations.
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/-/gmalScissile bondGA/ga/-/- (based on 12 cleavages)
weblogo
Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 0 0 0 4 6 4 0 0
Pro 0 0 0 0 0 0 0 0
Ala 0 0 0 2 5 3 0 0
Val 0 0 0 0 0 0 0 0
Leu 0 0 0 2 1 1 0 0
Ile 0 0 0 0 0 0 0 0
Met 0 0 0 3 0 1 0 0
Phe 0 0 0 1 0 1 0 0
Tyr 0 0 0 0 0 1 0 0
Trp 0 0 0 0 0 0 0 0
Ser 0 0 0 0 0 1 0 0
Thr 0 0 0 0 0 0 0 0
Cys 0 0 0 0 0 0 0 0
Asn 0 0 0 0 0 0 0 0
Gln 0 0 0 0 0 0 0 0
Asp 0 0 0 0 0 0 0 0
Glu 0 0 0 0 0 0 0 0
Lys 0 0 0 0 0 0 0 0
Arg 0 0 0 0 0 0 0 0
His 0 0 0 0 0 0 0 0