Summary for peptidase M20.010: DapE peptidase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

 

Names
MEROPS NameDapE peptidase
Other namesaspartyl dipeptidase, dapE g.p. (Escherichia coli), succinyl-diaminopimelate desuccinylase
Domain architecture
MEROPS Classification
Classification Clan MH >> Subclan (none) >> Family M20 >> Subfamily A >> M20.010
HolotypeDapE peptidase (Escherichia coli), Uniprot accession P0AED7 (peptidase unit: 1-375), MERNUM MER0001272
History Identifier created: MEROPS 6.5 (22 December 2003)
Activity
Catalytic typeMetallo
NC-IUBMBSubclass 3.4 (Peptidases) >> Sub-subclass 3.5.1 () >> Peptidase 3.5.1.18
EnzymologyBRENDA database
Pathways KEGGBiosynthesis of amino acids
KEGGLysine biosynthesis
KEGGMicrobial metabolism in diverse environments
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/-/DScissile bond-/-/-/- (based on 15 cleavages)
weblogo
Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 0 0 0 0 1 0 0 0
Pro 0 0 0 0 0 0 0 0
Ala 0 0 0 0 1 0 0 0
Val 0 0 0 0 1 0 0 0
Leu 0 0 0 0 1 0 0 0
Ile 0 0 0 0 0 0 0 0
Met 0 0 0 0 1 0 0 0
Phe 0 0 0 0 0 0 0 0
Tyr 0 0 0 0 1 0 0 0
Trp 0 0 0 0 0 0 0 0
Ser 0 0 0 0 1 0 0 0
Thr 0 0 0 0 1 0 0 0
Cys 0 0 0 0 1 0 0 0
Asn 0 0 0 0 1 0 0 0
Gln 0 0 0 0 0 0 0 0
Asp 0 0 0 15 1 0 0 0
Glu 0 0 0 0 1 0 0 0
Lys 0 0 0 0 1 0 0 0
Arg 0 0 0 0 1 0 0 0
His 0 0 0 0 1 0 0 0