Summary for peptidase M24.038: aminopeptidase P (Plasmodium falciparum-type)

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors

 

Names
MEROPS Nameaminopeptidase P (Plasmodium falciparum-type)
Other namesPfAPP
Domain architecture
MEROPS Classification
Classification Clan MG >> Subclan (none) >> Family M24 >> Subfamily B >> M24.038
Holotypeaminopeptidase P (Plasmodium falciparum-type) (peptidase unit: 457-711), MERNUM MER0027437
Activity
Catalytic typeMetallo
NC-IUBMBNot yet included in IUBMB recommendations.
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/-/-Scissile bondP/-/-/- (based on 22 cleavages)
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Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 0 0 0 1 0 0 1 0
Pro 0 0 0 1 22 1 0 0
Ala 0 0 0 1 0 0 0 0
Val 0 0 0 1 0 0 0 0
Leu 0 0 0 1 0 0 0 0
Ile 0 0 0 1 0 0 0 0
Met 0 0 0 1 0 0 0 0
Phe 0 0 0 2 0 0 1 1
Tyr 0 0 0 2 0 0 0 0
Trp 0 0 0 1 0 1 0 0
Ser 0 0 0 1 0 0 0 0
Thr 0 0 0 1 0 0 1 0
Cys 0 0 0 0 0 0 0 0
Asn 0 0 0 1 0 0 0 0
Gln 0 0 0 1 0 0 0 1
Asp 0 0 0 0 0 0 0 1
Glu 0 0 0 1 0 0 0 0
Lys 0 0 0 1 0 0 0 0
Arg 0 0 0 2 0 0 0 0
His 0 0 0 1 0 1 0 0