Summary for peptidase M28.003: aminopeptidase S (Streptomyces-type)

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors

 

Names
MEROPS Nameaminopeptidase S (Streptomyces-type)
Other namesaminopeptidase (Streptomyces griseus), Mername-AA022 peptidase, SGAP, SKAP
Domain architecture
MEROPS Classification
Classification Clan MH >> Subclan (none) >> Family M28 >> Subfamily A >> M28.003
Holotypeaminopeptidase S (Streptomyces-type) (Streptomyces griseus), Uniprot accession P80561 (peptidase unit: 46-329), MERNUM MER0002161
History Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.
Activity
Catalytic typeMetallo
PeplistIncluded in the Peplist with identifier PL00247
NC-IUBMBSubclass 3.4 (Peptidases) >> Sub-subclass 3.4.11 (Aminopeptidases) >> Peptidase 3.4.11.24
EnzymologyBRENDA database
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/-/LScissile bond-/-/-/- (based on 10 cleavages)
weblogo
Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 0 0 0 0 0 0 0 0
Pro 0 0 0 0 0 0 0 0
Ala 0 0 0 0 0 0 0 0
Val 0 0 0 0 0 0 0 0
Leu 0 0 0 8 1 0 0 0
Ile 0 0 0 0 0 0 0 0
Met 0 0 0 0 0 0 0 0
Phe 0 0 0 2 3 1 0 0
Tyr 0 0 0 0 1 0 0 0
Trp 0 0 0 0 1 0 0 0
Ser 0 0 0 0 1 0 0 0
Thr 0 0 0 0 0 0 0 0
Cys 0 0 0 0 0 0 0 0
Asn 0 0 0 0 0 0 0 0
Gln 0 0 0 0 0 0 0 0
Asp 0 0 0 0 0 0 0 0
Glu 0 0 0 0 0 0 0 0
Lys 0 0 0 0 0 0 0 0
Arg 0 0 0 0 1 0 0 0
His 0 0 0 0 1 0 0 0