Summary for peptidase M36.001: fungalysin

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors


MEROPS Namefungalysin
Other namesallergen Asp f 5 (Aspergillus fumigatus), elastinolytic metalloproteinase, Mep g.p. (Aspergillus flavus, A. fumigatus), MEP1 g.p. (Microsporum canis), MEP2 g.p. (Microsporum canis), MEP3 g.p. (Microsporum canis), neutral protease I (Aspergillus oryzae), NpI (Aspergillus oryzae)
Domain architecture
MEROPS Classification
Classification Clan MA >> Subclan MA(E) >> Family M36 >> Subfamily (none) >> M36.001
Holotypefungalysin (Aspergillus fumigatus), Uniprot accession P46075 (peptidase unit: 246-634), MERNUM MER0001400
History Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.
Catalytic typeMetallo
NC-IUBMBNot yet included in IUBMB recommendations.
PhysiologyProbably contributes to destruction of host tissues in lung infection.