Summary for peptidase M9A.007: Xaa-Trp aminopeptidase

Summary Distribution Literature Substrates Inhibitors

 

Names
MEROPS NameXaa-Trp aminopeptidase
Other namesaminopeptidase W, X-Trp aminopeptidase
MEROPS Classification
Classification Clan (unassigned) >> Subclan (unassigned) >> Family (unassigned) >> Subfamily (unassigned) >> M9A.007
History Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.
Activity
Catalytic typeMetallo
NC-IUBMBSubclass 3.4 (Peptidases) >> Sub-subclass 3.4.11 (Aminopeptidases) >> Peptidase 3.4.11.16
EnzymologyBRENDA database
PhysiologyProbable role in digestion of peptides in intestine and kidney glomerulus.
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/-/wScissile bondflw/-/-/- (based on 13 cleavages)
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Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 0 0 0 0 2 0 0 0
Pro 0 0 0 0 0 0 0 0
Ala 0 0 0 0 1 0 0 0
Val 0 0 0 0 0 0 0 0
Leu 0 0 0 1 3 0 0 0
Ile 0 0 0 0 0 0 0 0
Met 0 0 0 0 0 0 0 0
Phe 0 0 0 2 3 0 0 0
Tyr 0 0 0 1 1 0 0 0
Trp 0 0 0 3 3 0 0 0
Ser 0 0 0 0 0 0 0 0
Thr 0 0 0 0 0 0 0 0
Cys 0 0 0 0 0 0 0 0
Asn 0 0 0 0 0 0 0 0
Gln 0 0 0 0 0 0 0 0
Asp 0 0 0 2 0 0 0 0
Glu 0 0 0 1 0 0 0 0
Lys 0 0 0 0 0 0 0 0
Arg 0 0 0 0 0 0 0 0
His 0 0 0 0 0 0 0 0