Summary for peptidase S01.142: duodenase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors

 

Names
MEROPS Nameduodenase
Other namessheep mast cell proteinase-1
Domain architecture
MEROPS Classification
Classification Clan PA >> Subclan PA(S) >> Family S1 >> Subfamily A >> S01.142
Holotypeduodenase (Bos taurus), Uniprot accession P80219 (peptidase unit: 20-242), MERNUM MER0001641
History Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.
Activity
Catalytic typeSerine
PeplistIncluded in the Peplist with identifier PL00277
NC-IUBMBNot yet included in IUBMB recommendations.
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage patterndfp/-/p/kflyScissile bond-/l/-/d (based on 19 cleavages)
weblogo
Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 0 1 1 0 0 1 0 0
Pro 2 0 4 0 0 0 2 0
Ala 0 0 2 0 0 0 0 0
Val 1 0 1 0 1 0 2 0
Leu 0 3 2 3 1 3 1 0
Ile 1 0 0 0 1 1 0 0
Met 0 0 0 0 1 0 0 1
Phe 2 2 0 5 1 0 0 1
Tyr 0 1 0 2 2 0 0 0
Trp 0 0 0 0 0 0 0 0
Ser 0 1 0 0 0 0 0 0
Thr 0 0 1 0 0 0 0 0
Cys 0 0 0 0 0 0 1 1
Asn 0 0 0 0 0 0 0 0
Gln 0 1 1 0 0 0 0 0
Asp 5 0 1 0 0 0 0 3
Glu 0 1 0 0 0 0 1 2
Lys 0 1 0 8 1 2 1 0
Arg 0 1 0 1 1 0 0 0
His 0 1 0 0 2 2 0 0