Summary for peptidase S01.144: cercarial elastase (Schistosoma sp.)

Summary Alignment Sequences Sequence features Distribution Literature Substrates Inhibitors


MEROPS Namecercarial elastase (Schistosoma sp.)
Other namesSmCE
Domain architecture
MEROPS Classification
Classification Clan PA >> Subclan PA(S) >> Family S1 >> Subfamily C >> S01.144
Holotypecercarial elastase (Schistosoma sp.) (Schistosoma mansoni), Uniprot accession P12546 (peptidase unit: 1-264), MERNUM MER0003620
History Identifier created: MEROPS 3.02 (25 June 1998)
Catalytic typeSerine
NC-IUBMBNot yet included in IUBMB recommendations.
Cleavage site specificity Explanation of how to interpret specificity from combinatorial substrates can be found here.
Specificity from combinatorial peptides
Organism comment P4 P3 P2 P1 P1' P2' P3' P4' optimal substrate fluorophore or acceptor-donor pair Reference
Schistosoma mansoi recombinant S/T/broad W/Y/broad P/A L/n/F - - - - SWPL ACC Salter et al., 2002
Schistosoma mansoni recombinant T/S/broad S/F/W/broad P L/n/F - - - - TSPL ACC Salter et al., 2002