Summary for peptidase S01.154: pancreatic endopeptidase E

Summary Alignment Tree Sequences Sequence features Distribution Literature Human EST Mouse EST Substrates Inhibitors Pharma

 

Names
MEROPS Namepancreatic endopeptidase E
Other namescattle subunit III, CELA3A g.p. (Homo sapiens), cholesterol-binding proteinase, elastase IIIA (Homo sapiens), elastase 3A (Homo sapiens), protease E, pancreatic endopeptidase E form A (Homo sapiens)
Domain architecture
MEROPS Classification
Classification Clan PA >> Subclan PA(S) >> Family S1 >> Subfamily A >> S01.154
Holotypepancreatic endopeptidase E (Homo sapiens), Uniprot accession P09093 (peptidase unit: 29-270), MERNUM MER0000149
History Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.
Activity
Catalytic typeSerine
PeplistIncluded in the Peplist with identifier PL00284
NC-IUBMBSubclass 3.4 (Peptidases) >> Sub-subclass 3.4.21 (Serine endopeptidases) >> Peptidase 3.4.21.70
EnzymologyBRENDA database
Activity statushuman: active (Bieth, 2004)
mouse: active (Kokai-Kun et al., 2000)
Pathways KEGGPancreatic secretion
KEGGProtein digestion and absorption
Other databases WIKIPEDIAhttp://en.wikipedia.org/wiki/Pancreatic_elastase
Human genetics
Gene symbol Locus Megabases Ensembl Entrez gene Gene Cards OMIM
CELA3A 1p36.12 ENSG00000142789 10136 ELA3A