Summary for peptidase S01.262: streptogrisin B

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors

 

Names
MEROPS Namestreptogrisin B
Other namesalkaline proteinase C, elastase-like enzyme III, guanidine-stable chymoelastase, PNPA hydrolase II, pronase elastase, SGP1, SGPB, Streptomyces griseus protease 1, Streptomyces griseus protease B
Domain architecture
MEROPS Classification
Classification Clan PA >> Subclan PA(S) >> Family S1 >> Subfamily E >> S01.262
Holotypestreptogrisin B (Streptomyces griseus), Uniprot accession P00777 (peptidase unit: 114-299), MERNUM MER0000252
History Identifier created: MEROPS 3.30 (20 July 1999)
Activity
Catalytic typeSerine
PeplistIncluded in the Peplist with identifier PL00328
NC-IUBMBSubclass 3.4 (Peptidases) >> Sub-subclass 3.4.21 (Serine endopeptidases) >> Peptidase 3.4.21.81
EnzymologyBRENDA database
Proteolytic eventsCutDB database (1 cleavage)
BiotechnologyA component of Pronase.
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage patterna/A/P/flaScissile bond-/-/-/- (based on 14 cleavages)
weblogo
Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 0 1 1 0 0 0 1 1
Pro 1 0 6 0 0 0 0 0
Ala 4 7 0 2 1 1 1 0
Val 0 0 0 0 1 0 1 0
Leu 0 0 0 4 0 0 0 0
Ile 0 0 0 0 1 0 0 0
Met 0 0 0 1 0 0 0 0
Phe 1 0 0 6 0 0 0 0
Tyr 0 0 0 1 0 0 0 0
Trp 0 0 0 0 0 0 0 0
Ser 0 0 0 0 0 1 0 0
Thr 0 1 0 0 0 0 0 0
Cys 0 0 0 0 0 0 0 0
Asn 0 0 0 0 0 0 0 0
Gln 0 0 0 0 0 0 0 0
Asp 0 0 0 0 0 0 0 0
Glu 0 0 0 0 0 0 0 1
Lys 0 0 1 0 0 0 0 0
Arg 0 0 1 0 0 0 0 0
His 1 0 0 0 0 1 0 0