Summary for peptidase S01.267: streptogrisin E

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors

 

Names
MEROPS Namestreptogrisin E
Other namesglutamyl endopeptidase (Streptomyces fradiae), glutamyl endopeptidase II (Streptomyces sp.), Streptomyces griseus protease E (SGPE), SFase endopeptidase (Streptomyces fradiae)
Domain architecture
MEROPS Classification
Classification Clan PA >> Subclan PA(S) >> Family S1 >> Subfamily E >> S01.267
Holotypestreptogrisin E (Streptomyces griseus), Uniprot accession Q07006 (peptidase unit: 1-187), MERNUM MER0000254
History Identifier created: MEROPS 3.30 (20 July 1999)
Activity
Catalytic typeSerine
PeplistIncluded in the Peplist with identifier PL00330
NC-IUBMBSubclass 3.4 (Peptidases) >> Sub-subclass 3.4.21 (Serine endopeptidases) >> Peptidase 3.4.21.82
EnzymologyBRENDA database
BiotechnologyA component of Pronase.
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage patternfg/A/A/EScissile bondVa/F/-/D (based on 23 cleavages)
weblogo
Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 4 0 0 0 0 0 0 0
Pro 1 0 2 0 0 0 0 0
Ala 2 18 18 2 4 1 0 0
Val 1 1 1 0 14 1 0 0
Leu 0 0 0 0 0 0 0 0
Ile 0 0 0 0 0 0 0 0
Met 0 0 0 0 0 0 0 0
Phe 9 1 1 0 0 15 0 0
Tyr 0 0 0 0 0 0 0 0
Trp 0 0 0 0 0 0 0 0
Ser 1 1 0 0 1 1 0 0
Thr 0 0 0 0 0 0 0 0
Cys 0 0 0 0 0 0 0 0
Asn 0 0 0 0 0 0 0 0
Gln 0 0 0 0 0 0 0 0
Asp 1 0 0 0 0 0 2 18
Glu 0 0 0 21 0 0 0 0
Lys 0 0 0 0 0 0 0 0
Arg 0 1 1 0 1 0 0 0
His 0 0 0 0 0 0 0 0