Summary for peptidase S01.422: fibrinolytic enzyme A (Annelida-type)

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors

 

Names
MEROPS Namefibrinolytic enzyme A (Annelida-type)
Other namesapoptosis-related serine protease (Eisenia fetida), ARSP1 peptidase (Eisenia fetida), earthworm fibrinolytic enzyme EfP-I (Eisenia fetida), EfP-I-1, EfP-I-2, EfP-II-1, EfP-II-2
Domain architecture
MEROPS Classification
Classification Clan PA >> Subclan PA(S) >> Family S1 >> Subfamily A >> S01.422
Holotypefibrinolytic enzyme A (Annelida-type) (Lumbricus bimastus) (peptidase unit: 1-242), MERNUM MER0005281
History Identifier created: MEROPS 6.1 (10 January 2003)
Activity
Catalytic typeSerine
NC-IUBMBNot yet included in IUBMB recommendations.
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage patterngl/-/-/vScissile bondgf/-/-/- (based on 19 cleavages)
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Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 4 1 4 1 4 2 1 0
Pro 0 0 1 0 0 1 0 1
Ala 1 3 1 2 0 0 1 1
Val 1 2 0 5 0 0 2 4
Leu 3 1 2 0 2 2 1 1
Ile 0 0 1 1 0 0 0 0
Met 0 0 1 0 0 0 1 0
Phe 0 1 2 1 3 2 0 0
Tyr 0 1 0 2 0 3 1 0
Trp 0 0 0 0 0 0 0 0
Ser 0 0 0 2 0 1 0 1
Thr 0 0 0 0 1 0 1 1
Cys 0 1 0 0 1 1 0 0
Asn 0 1 0 0 1 0 1 0
Gln 1 0 1 0 0 1 0 0
Asp 0 0 2 0 0 0 0 0
Glu 1 2 1 0 0 0 2 2
Lys 0 1 0 0 0 0 1 1
Arg 1 1 1 4 0 0 0 1
His 0 1 0 1 1 0 1 0