Summary for peptidase S06.003: Tsh peptidase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Inhibitors

 

Names
MEROPS NameTsh peptidase
Other namesAusI g.p. (Neisseria meningitidis), hemoglobin protease (Hbp), meningococcal serine protease A, MspA g.p. (Neisseria meningitidis), vacuolating autotransporter toxin (Vat), Vat peptidase (Escherichia coli)
Domain architecture
MEROPS Classification
Classification Clan PA >> Subclan PA(S) >> Family S6 >> Subfamily (none) >> S06.003
HolotypeTsh peptidase (Escherichia coli), Uniprot accession Q47692 (peptidase unit: 53-780), MERNUM MER0000281
History Identifier created: MEROPS 3.1 (22 December 1998)
Activity
Catalytic typeSerine
NC-IUBMBNot yet included in IUBMB recommendations.
Pharmaceutical relevanceOne of the plasmid-encoded autotransporter proteins of enteropathogenic Escherichia coli, and may be a virulence factor; cleaves human coagulation factor V.