Summary for peptidase S08.003: subtilisin lentus

Summary Alignment Sequences Sequence features Distribution Structure Literature Substrates Inhibitors

 

Names
MEROPS Namesubtilisin lentus
Other namesAprB peptidase (Bacillus sp. B001), Esperase, Maxacal, protease PB92 (Bacillus sp.), Savinase, subtilisin 309, subtilisin (Bacillus lentus variant), subtilisin BL, subtilisin MC3
Domain architecture
MEROPS Classification
Classification Clan SB >> Subclan (none) >> Family S8 >> Subfamily A >> S08.003
Holotypesubtilisin lentus (Bacillus lentus), Uniprot accession P29600 (peptidase unit: 1-269), MERNUM MER0001906
History Identifier created: MEROPS 3.02 (25 June 1998)
Activity
Catalytic typeSerine
PeplistIncluded in the Peplist with identifier PL00343
NC-IUBMBNot yet included in IUBMB recommendations.
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/-/lScissile bond-/l/-/- (based on 16 cleavages)
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Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 2 1 2 0 1 1 0 2
Pro 0 0 2 0 0 0 0 1
Ala 1 0 1 1 2 1 1 1
Val 3 1 4 0 1 1 2 1
Leu 1 2 1 4 0 5 1 2
Ile 0 1 0 0 0 0 0 0
Met 0 0 0 0 0 0 0 0
Phe 2 0 0 2 1 0 0 0
Tyr 3 0 0 0 2 2 2 0
Trp 0 0 0 0 0 0 0 0
Ser 0 2 1 1 2 0 2 1
Thr 0 1 0 0 0 0 1 0
Cys 0 2 1 2 1 1 3 0
Asn 1 0 1 0 1 0 0 1
Gln 1 2 1 1 1 1 0 1
Asp 0 0 0 0 0 1 0 0
Glu 1 2 0 3 0 2 0 2
Lys 0 0 0 1 0 0 0 0
Arg 0 1 0 0 0 0 1 0
His 1 0 2 0 2 0 0 1