Summary for peptidase S08.009: subtilisin Ak1

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

 

Names
MEROPS Namesubtilisin Ak1
Other namesF1 protease (Bacillus stearothermophilus), Mername-AA054 peptidase
Domain architecture
MEROPS Classification
Classification Clan SB >> Subclan (none) >> Family S8 >> Subfamily A >> S08.009
Holotypesubtilisin Ak1 (Geobacillus stearothermophilus), Uniprot accession Q45670 (peptidase unit: 130-400), MERNUM MER0000332
History Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.
Activity
Catalytic typeSerine
PeplistIncluded in the Peplist with identifier PL00345
NC-IUBMBNot yet included in IUBMB recommendations.
Proteolytic eventsCutDB database (3 cleavages)
PhysiologyProbably contributes to nutrition of organism.
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/a/-Scissile bond-/-/-/- (based on 12 cleavages)
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Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 0 0 0 1 0 0 0 1
Pro 0 0 1 0 0 0 0 0
Ala 1 3 4 3 1 0 0 0
Val 1 1 1 1 0 0 1 0
Leu 0 1 1 2 0 3 0 1
Ile 0 0 0 0 0 0 0 0
Met 0 0 0 0 0 0 0 0
Phe 1 0 0 2 0 0 0 0
Tyr 0 1 0 0 1 0 1 0
Trp 0 0 0 0 0 0 0 0
Ser 0 0 0 0 0 0 0 0
Thr 0 0 0 0 0 0 0 0
Cys 0 0 0 0 0 0 0 0
Asn 0 0 1 0 0 0 0 0
Gln 0 0 0 1 0 0 0 0
Asp 0 0 0 0 0 0 0 0
Glu 0 1 0 1 0 0 0 0
Lys 0 0 0 0 0 0 0 0
Arg 0 0 0 0 0 0 0 0
His 1 0 0 0 1 0 0 0