Summary for peptidase S08.057: thermomycolin

Summary Alignment Sequences Sequence features Distribution Literature Substrates

 

Names
MEROPS Namethermomycolin
Other namesthermomycolase
Domain architecture
MEROPS Classification
Classification Clan SB >> Subclan (none) >> Family S8 >> Subfamily A >> S08.057
Holotypethermomycolin (Malbranchea cinnamomea), Uniprot accession P13858 (peptidase unit: 1-34), MERNUM MER0001998
History Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.
Activity
Catalytic typeSerine
PeplistIncluded in the Peplist with identifier PL00355
NC-IUBMBSubclass 3.4 (Peptidases) >> Sub-subclass 3.4.21 (Serine endopeptidases) >> Peptidase 3.4.21.65
EnzymologyBRENDA database
Proteolytic eventsCutDB database (22 cleavages)
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/-/-Scissile bond-/-/-/- (based on 28 cleavages)
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Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 1 3 2 2 3 0 0 0
Pro 0 0 2 0 0 3 0 1
Ala 1 1 3 2 1 1 2 2
Val 3 1 3 0 1 0 2 0
Leu 1 2 3 5 2 5 1 2
Ile 0 0 0 0 0 0 0 0
Met 0 0 0 1 1 1 2 0
Phe 1 4 1 3 2 1 1 0
Tyr 3 2 1 2 3 3 1 1
Trp 0 1 1 1 2 0 1 0
Ser 2 1 4 2 1 2 3 1
Thr 1 0 2 1 2 3 2 2
Cys 0 0 0 0 0 0 0 0
Asn 0 0 0 0 2 1 1 3
Gln 2 4 1 4 0 2 1 2
Asp 3 1 2 1 3 1 2 2
Glu 1 1 0 2 0 0 0 1
Lys 1 1 1 1 0 0 2 2
Arg 1 2 0 1 2 2 2 3
His 1 1 0 0 0 0 0 0